ITP Conference 2023 - Speakers
... in national ITP guideline initiatives. Dr. Grace’s clinical and research interests are focused on improving outcomes of children with immune cytopenias and rare congenital hemolytic anemias.
Craig ...
PDSA E-News: August 31, 2022
... disorder thalassemia trait, or any of potentially serious causes of microangiopathic hemolytic anemia in which red cells are fragmented in the circulation.
Evans syndrome is a more severe autoimmune ...
PDSA e-News: September 30, 2021
... Seven stopped using avatrombopag for the following reasons: two stopped responding to treatment, one started rituximab because of worsening autoimmune hemolytic anemia, two experienced toxicity, and two ...
Single-dose Anti-CD20 Antibody With Bortezomib for Relapsed Refractory Autoimmune Hemolytic Anemia (RRAIHA01)
... type of chemotherapy) works in the treatment of relapsed refractory autoimmune hemolytic anemia. The study is also open to patients who have secondary Evans syndrome. Participants must be adults between ...
ITP Warrior - Anne Marie
... six, where they discovered I had AIHA – auto-immune hemolytic anemia. I had a virus and my immune system started attacking both the virus and my red cells. My red cell count was at 3,000 and I needed 11 ...
PDSA e-News: March 31, 2019
... hemolytic anemia as a result of the drug’s effect on the body. This outcome suggests that these immune checkpoints may play a significant role in the development of certain hematologic disorders, such ...
PDSA e-News: December 28, 2018
... only 16% of patients developing side effects including hemolytic anemia (4%) or symptomatic methemoglobinemia (4%), and demonstrated decent patient response.
Comment from PDSA Medical Advisor: Dapsone ...
Severe Immune Cytopenia Registry Www.Sic-reg.Org (sic-reg)
Prospective registry study for children and young adults with severe immune cytopenias (persisting/chronic immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome) to improve the management, ...
Autoimmune Cytopenias : Midi-Pyrenees Registry (CARMEN)
CARMEN is a clinical registry of all incident adult Immune thrombocytopenia (ITP) and Autoimmune Hemolytic anemia (AIHA) patients in the Midi-Pyrenees region (South of France). It is aimed at describing ...
Sanofi’s Cablivi cleared for rare bleeding disorder (TTP)
"The European Commission has authorised Cablivi (caplacizumab) as the first therapeutic specifically indicated for the treatment of adults experiencing an episode of aTTP.
The condition is a life-threatening, ...
PDSA e-News: April 20, 2018
... hemolytic anemia, a rare disease for which there are no approved therapies.”
The approval comes after a Phase two study, two phase three studies using placebo and a long-term study analyzing the effects ...
Low Platelets Associated with Other Autoimmune Diseases
... thrombocytopenia (ITP) and autoimmune destruction of red blood cells (hemolytic anemia).
Resources and research providing insight into Evans syndrome include:
Evans Syndrome Foundation
Medscape ...
Intravenous Immunoglobulin Therapy (IVIG)
... blood clots8, hemolytic anemia, pulmonary edema and aseptic meningitis syndrome.5
Patients who are IgA (immunoglobulin A) deficient have a greater chance of developing anaphylactic shock.1 IVIG can ...
HCP Resources
... prior rituximab: post-hoc analysis of the EXTEND study
Recent advances in the mechanisms and treatment of immune thrombocytopenia
Fostamatinib for the treatment of warm antibody autoimmune hemolytic ...
Platelet E-News: November 27, 2013
...
Note: For more information on genetic causes of low platelets see: http://www.pdsa.org/about-itp/and-families.html
Wang Z et al. “Specific macrothrombocytopenia/hemolytic anemia associated with sitosterolemia.” ...
Platelet E-News: January 21, 2011
... rozrolimupab (SYM001), a polyclonal composed of 25 different antibodies to Rhesus D (anti-D), to be used for the treatment of ITP and prevention of hemolytic disease in newborns. Now Sobi has returned ...
Platelet E-News: October 25, 2010
... CYTOPENIAS
In a study of 19 patients, 11 with ITP and 8 with autoimmune hemolytic anemia (low red cells), researchers in Mexico found that all of the patients responded to a concurrent treatment of rituximab ...
Platelet E-News – March 17, 2003
... involvement, autoimmune hemolytic anemia, anti-double-stranded DNA, and anti-phospholipid antibody.
“Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and ...
Platelet E-News – November 24, 2009
...
ITP Research and Treatments
EVANS SYNDROME IS OFTEN ASSOCIATED WITH OTHER DISORDERS
Evans Syndrome (ES) is the combination of ITP and autoimmune hemolytic anemia (low red cell ...
Platelet E-News – March 23, 2009
... risk for autoimmune hemolytic anemia. Patients with untreated HCV had a 1.7 fold increased risk of developing ITP and HCV patients treated with interferon alpha had a 2.4-fold increased risk, compared ...
Information About Other Platelet Disorders
...
http://bloodjournal.hematologylibrary.org/content/106/5/1532.long
Thrombotic Thrombocytopenic Purpura (TTP) / Hemolytic Uremic Syndrome (HUS)
These related diseases are both characterized by low ...
