The goal of this study is to better understand the diagnosis pattern and treatment options of various autoimmune conditions, including autoimmune hemolytic anemia, immune thrombocytopenia, and chronic ...
... in national ITP guideline initiatives. Dr. Grace’s clinical and research interests are focused on improving outcomes of children with immune cytopenias and rare congenital hemolytic anemias.
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... disorder thalassemia trait, or any of potentially serious causes of microangiopathic hemolytic anemia in which red cells are fragmented in the circulation.
Evans syndrome is a more severe autoimmune ...
... Seven stopped using avatrombopag for the following reasons: two stopped responding to treatment, one started rituximab because of worsening autoimmune hemolytic anemia, two experienced toxicity, and two ...
... type of chemotherapy) works in the treatment of relapsed refractory autoimmune hemolytic anemia. The study is also open to patients who have secondary Evans syndrome. Participants must be adults between ...
... six, where they discovered I had AIHA – auto-immune hemolytic anemia. I had a virus and my immune system started attacking both the virus and my red cells. My red cell count was at 3,000 and I needed 11 ...
... hemolytic anemia as a result of the drug’s effect on the body. This outcome suggests that these immune checkpoints may play a significant role in the development of certain hematologic disorders, such ...
... only 16% of patients developing side effects including hemolytic anemia (4%) or symptomatic methemoglobinemia (4%), and demonstrated decent patient response.
Comment from PDSA Medical Advisor: Dapsone ...
Prospective registry study for children and young adults with severe immune cytopenias (persisting/chronic immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome) to improve the management, ...
CARMEN is a clinical registry of all incident adult Immune thrombocytopenia (ITP) and Autoimmune Hemolytic anemia (AIHA) patients in the Midi-Pyrenees region (South of France). It is aimed at describing ...
"The European Commission has authorised Cablivi (caplacizumab) as the first therapeutic specifically indicated for the treatment of adults experiencing an episode of aTTP.
The condition is a life-threatening, ...
... hemolytic anemia, a rare disease for which there are no approved therapies.”
The approval comes after a Phase two study, two phase three studies using placebo and a long-term study analyzing the effects ...
... syndrome is the combination of autoimmune thrombocytopenia (ITP) and autoimmune destruction of red blood cells (hemolytic anemia).
Resources for Evans syndrome include:
http://evanssyndromefoundation.org/ ...
... blood clots8, hemolytic anemia, pulmonary edema and aseptic meningitis syndrome.5
Patients who are IgA (immunoglobulin A) deficient have a greater chance of developing anaphylactic shock.1 IVIG can ...
...
Note: For more information on genetic causes of low platelets see: http://www.pdsa.org/about-itp/and-families.html
Wang Z et al. “Specific macrothrombocytopenia/hemolytic anemia associated with sitosterolemia.” ...
... rozrolimupab (SYM001), a polyclonal composed of 25 different antibodies to Rhesus D (anti-D), to be used for the treatment of ITP and prevention of hemolytic disease in newborns. Now Sobi has returned ...
... CYTOPENIAS
In a study of 19 patients, 11 with ITP and 8 with autoimmune hemolytic anemia (low red cells), researchers in Mexico found that all of the patients responded to a concurrent treatment of rituximab ...
... involvement, autoimmune hemolytic anemia, anti-double-stranded DNA, and anti-phospholipid antibody.
“Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and ...
...
ITP Research and Treatments
EVANS SYNDROME IS OFTEN ASSOCIATED WITH OTHER DISORDERS
Evans Syndrome (ES) is the combination of ITP and autoimmune hemolytic anemia (low red cell ...
... risk for autoimmune hemolytic anemia. Patients with untreated HCV had a 1.7 fold increased risk of developing ITP and HCV patients treated with interferon alpha had a 2.4-fold increased risk, compared ...
...
http://bloodjournal.hematologylibrary.org/content/106/5/1532.long
Thrombotic Thrombocytopenic Purpura (TTP) / Hemolytic Uremic Syndrome (HUS)
These related diseases are both characterized by low ...
