The Combination of ATRA and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia

This is a multi-center, randomized, open-label trial through Peking University People's Hospital investigating how the combination of oral all-trans retinoic acid (ATRA) and high-dose dexamethasone vs high-dose dexamethasone alone as first-line treatment immune thrombocytopenia. Eligibility is restricted to adult patients between 18-70 years of age who have newly diagnosed ITP, and a platelet count under 30 x 109/L OR significant bleeding and a platelet count less than 50 x 109/L.



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