RP% Measurement by FCM as a Diagnostic Test for ITP

Immature platelets—also termed reticulated platelets (RP)—are platelets newly released into the circulation, and have been associated with a variety of pathological bleeding events including primary immune thrombocytopenia (ITP). The diagnosis of primary ITP is based on differential diagnosis and the measurement of RP% can serve as an alternative diagnostic test that are useful in daily practice. This study aims at distinguishing primary ITP from other thrombocytopenic disorders, especially aplastic (hypoplastic) or chemotherapy-induced thrombocytopenia by flow cytometry.




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