Here's the story, want to know if anyone has a similar experience.
I started Promacta in June with no side-effects, 50mg per day. After about 6 weeks I was lowered to 25mg per day. In December my platelets dropped back to nearly zero. I was upped back to 50mg per day and took a four day dexamethasone pulse. About a week after stopping the steroids I started to get diarrhea. It's been... 6 weeks now and the diarrhea remains. There's no stomach pain or urgency to go, it's just that when I do go it's straight liquid or very loose.
Could this be a result of the Promacta, even though it didn't cause this initially?
Diarrhea is listed as a side effect for Promacta. I get Nplate injections and have a bit of loose bowels with it, but since the injection is only once per week, the bowel upset is usually only for one day- its not a problem for me. But what you are describing sounds unhealthy- be sure to drink lots of water so you don't get dehydrated. Have you spoken to your doctor about it? I'd guess the only way to know for sure is to quit Promacta under your doctor's supervision and see if it clears up. But talk to your doctor of course and get his/her advice. There may be something else you can do.
Odd that it began only after taking a dexy pulse. I wonder if your digestive balance was upset by the dexamethasone. I find that drug to be harsh and hope to never take it again. I was on Promacta 4 different times and quit 4 times due to intolerable side effects. For me it was brain fog, headache, memory lapse, lack of imagination- the side effects were always around my thinking/head. good luck!
I have irritable bowel syndrome, so it's hard for me to tell--but, after 3 months on Promacta, I don't think Promacta has increased or altered my diarrhea. Anxiety and the prednisone withdrawal, on the other hand, seem to affect it.
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